Question: iPSC reprogramming efficiency optimization protocols

[confound] Has any delivery method been tested with enough independent replicates under fully matched factor-cocktail-and-handling conditions to establish a within-class noise floor for the retroviral, lentiviral, Sendai, episomal, or mRNA classes specifically, the way Manzini 2015 incidentally did for electroporation (3.77-to-629.6-fold across three patients)?